منابع مشابه
Growth Hormone in Turner Syndrome
We studied the adult height (AH) outcome, and factors likely to influence it, in Turner Syndrome (TS) girls treated with growth hormone (GH). A total of 25 TS girls treated with GH were compared with 10 TS girls not treated with GH. The percentage of girls who achieved normal third percentile was determined. Projected AH (PAH) was calculated according to height standard deviation score (HSDS) a...
متن کاملGrowth hormone therapy in patients with Turner syndrome.
This article summarizes the published data on final height after growth-promoting therapy in Turner syndrome. Using growth hormone (GH) doses ranging between 0.5 and 1.2 IU/kg/week, final height after therapy is improved by 1.5-9.3 cm [final height after therapy vs. projected adult height (PAH)] within various studies. There is no obvious GH dose-response relationship, but a better estimated be...
متن کاملRecombinant human growth hormone in the treatment of Turner syndrome
Turner syndrome (TS) is a common chromosomal disorder in women that is associated with the absence of one of the X chromosomes. Severe short stature and a lack of pubertal development characterize TS girls, causing psychosocial problems and reduced bone mass. The growth impairment in TS seems to be due to multiple factors including an abnormal growth hormone (GH) - insulin-like growth factor (I...
متن کاملHeight in Turner syndrome: does growth hormone therapy have impact?
Sir Short stature is a cardinal feature of Turner syndrome. We examined height outcome and its relation to growth hormone therapy in Irish girls with Turner syndrome. In those with Turner syndrome (TS), the adult stature is an average 20 cm shorter than the general population 1 . By 15 years of age, the average height of an untreated girl with TS is equivalent to that of only a 9.5-year-old gir...
متن کاملRecombinant growth hormone for children and adolescents with Turner syndrome.
BACKGROUND Turner syndrome (TS) affects about one in 1500 to 2500 live-born females. One of the most prevalent and salient features of the syndrome is extremely short stature. Untreated women are approximately 20 to 21 cm shorter than normal women within their respective populations. Recombinant human growth hormone (hGH) has been used to increase growth and final height in girls who have Turne...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2001
ISSN: 0003-9888
DOI: 10.1136/adc.84.6.525m